Natalia Khuri, MBA, PhD | HOME | COURSES | PUBLICATIONS

HIGHER EDUCATION RESEARCH

S. Khuri, M. Van Hoven, N. Khuri. Increasing the Capacity of STEM Workforce: Minor in Bioinformatics. Proceedings of 2017 ACM SIGCSE, Seattle, March 8-11, 2017.

S. Khuri, N. Khuri, A. Picker, A. Budd, S. Chabanis-Davidson, J. Willingale-Theune. Discovering Bioinformatics: a protein in the World Wide Web. On-line Teacher Training (ELLS) TeachingBASE, EMBL

Bioinformatics Education Research Machine Learning Regulatory Science

MACHINE LEARNING FOR IN SILICO LIGAND DISCOVERY

N. Khuri, A. Zur, M. Wittwer, L. Lin, S.W. Yee, A. Sali, K. Giacomini. Computational Discovery and Experimental Validation of Inhibitors of the Human Intestinal Transporter, OATP2B1. Journal of Chemical Information and Modeling, May 31, 2017.

E. C. Chen, N. Khuri, X. Liang, A. Stecula, Y. Huang, A. Sali, K. M. Giacomini. Discovery of orthosteric and allosteric ligands of the Organic Cation Transporter, OCT1. Journal of Medicinal Chemistry, February 23, 2017.

A. Schlessinger, N. Khuri, K. Giacomini, A. Sali. Molecular modeling and ligand docking for Solute Carrier (SLC) transporters. Current Topics in Medicinal Chemistry 13, 843-856, 2013.

M.B. Wittwer, A.A. Zur, N. Khuri, Y. Kido, A. Kosaka, X. Zhang, K.M. Morrissey, A. Sali, Y. Huang, K.M. Giacomini. Discovery of potent, selective multidrug and toxin extrusion Transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. Journal of Medicinal Chemistry 56, 781-795, 2013.

A. Schlessinger, M.B. Wittwer, A. Dahlin, N. Khuri, M. Bonomi, H. Fan, K. Giacomini, A. Sali. High Selectivity of the gamma-Aminobutyric Acid Transporter 2 (GAT-2, SLC6A13) Revealed by Structure-based Approach. Journal of Biological Chemistry 287, 37745-37756, 2012.

BIOINFORMATICS

B. Webb, N. Eswar, H. Fan, N. Khuri, U. Pieper, G. Dong, A. Sali. Comparative Modeling of Drug Target Proteins. Chemistry, Molecular Sciences and Chemical Engineering. Ed: J. Reedijk, Elsevier, Waltham, MA, 2014.

U. Pieper, B. Webb, G.Q. Dong, D. Schneidman-Duhovny, H. Fan, S.J. Kim, N. Khuri, Y. Spill, P. Weinkam, M. Hammel, J. Tainer, M. Nilges, A. Sali. ModBase, a database of annotated comparative protein structure models, and associated resources. Nucleic Acids Research, 2014 Jan 1;42(1):D336-46.

D. Bhaya, A.R. Grossman, A.S. Steunou, N. Khuri, F.M. Cohan, N. Hamamura, M. C. Melendrez, M. M. Bateson, D. M. Ward, J.F. Heidelberg. Genomic, metagenomic and functional analyses of cyanobacteria from hot-spring microbial mats reveal an unexpected diversity in nutrient utilization strategies. ISME J: 1(8):703-13, 2007.

REGULATORY SCIENCE

R. Altman, S. Prabhu, A. Sidow, J. Zook, R. Goldfeder, D. Litwack, E. Ashley, G. Asimenos, C. Bustamante, K. Donigan, K. Giacomini, E. Johansen, N. Khuri, E. Lee, X. Liang, M. Salit, O. Serang, Z. Tezak, D. Wall, E. Mansfield, T. Kass-Hout. A research roadmap for next-generation sequencing informatics. Science Translational Medicine volume 8 (335), pp. 335ps10, 2016.

R. Altman, N. Khuri, M. Sali, K. Giacomini. Unmet needs: Research helps regulators do their jobs. Science Translational Medicine volume 7, Issue 315, pp. 315ps22, 2015.

updated 08/18/2017